CBI offers a range of infection modeling services for the purposes of identification of novel anti-infective agents, particularly MRSA, vancomycin-resistant staph, fungi and gram positive organisms. In addition to standard infection models, CBI offers customized and unique infection models. We also provide toxicity, safety, in vitro, and pharmacokinetic (including perilymph) studies to support development of anti-infectives. We offer unique routes of administration including intracerebral, intracolonic, intravesicular, intraocular, intraotic, dermal, and intraosseus.
- Mouse protection test
- Neutropenic thigh abscess and cytodex bead abscess
- Bacterial endocarditis in rabbits
- Dermal and topical infection
- Bacterial pneumonia, including Streptococcus and Pseudomonas
- Burn, wound, suture, foreign body implant infection
- Ocular and otic infection
- Oral infection models (food-borne pathogens)
- Renal infection, blood borne and ascending
- Sepsis- LPS, CLP, CASP
- Clostridial diarrhea
- Fungal studies
- Meningitis and bone infection
- Customized infection model development
- Histopathology and special bacterial stains
- Toxicity, safety and pharmacokinetic in vitro studies to support efficacy studies
- Customized and specially licensed cell lines
- Custom bacterial strains
For more information, check out blog on infection modeling.
