Heymann Nephritis: Immune-mediated FX-1A-induced glomerular nephritis in rats
Immune-mediated FX-1A-induced glomerular nephritis in rats is an excellent translational model of immune mediated membranous glomerular nephritis in humans. Administration of sheep antibody to rat proximal tubular epithelial cell brush border antigen… Read More
Optical Coherence Tomography OCT in Rodent Diabetic Retinopathy
One of our most popular uses of OCT is in rodent diabetic retinopathy. We have developed an optimized experimental design with sophisticated OCT, funduscopic and histopathologic determinants to analyze the potential effects… Read More
Efficacy models and the Importance of Optical Coherence Tomography (OCT)
OCT is also important in efficacy models: • Choroidal neovascularization • Oxygen-induced retinopathy • Subretinal injections and deposits • Light induced retinopathy • Retinal degeneration • Ocular inflammation of the anterior and… Read More